Company pulls drugs aimed at treating heart attacks and strokes over nitrosamine contamination
Pfizer headquarters in New York, March 1, 2022. © Eduardo MunozAlvarez/VIEWpress via Getty Images
The drug company Pfizer announced Monday it was recalling several lots of its drug Accuretic along with two generic versions, citing unacceptably high levels of a substance that US regulators said could cause cancer. People who used the blood pressure drugs to reduce the risk of stroke and heart attacks were advised to find alternatives.
Several “tainted” lots of Accuretic and two authorized generic versions of the drug (quinapril HCl/hydrochlorothiazide) distributed by Greenstone were found to have levels of N-nitroso-quinapril above the Acceptable Daily Intake (ADI) set by US regulators, Pfizer said in a statement. The company provided lot numbers and other information to identify the bad lots of the drugs.
While everyone is exposed to some level of nitrosamines, these “impurities may increase the risk of cancer if people are exposed to them above acceptable levels over long periods of time,” Pfizer noted.